| Luxembourg to Schijndel | 141.88 mi (228.33 km) |
| Luxembourg to Schinnen | 93.12 mi (149.86 km) |
| Luxembourg to Schoonhoven | 170.98 mi (275.17 km) |
| Luxembourg to Simpelveld | 84.66 mi (136.25 km) |
| Luxembourg to Sint Anthonis | 139.59 mi (224.66 km) |
| Luxembourg to Sint Willebrord | 150.02 mi (241.43 km) |
| Luxembourg to Sint-Michielsgestel | 144.40 mi (232.39 km) |
| Luxembourg to Sint-Oedenrode | 138.04 mi (222.15 km) |
| Luxembourg to Sittard | 96.63 mi (155.52 km) |
| Luxembourg to Sliedrecht | 163.63 mi (263.34 km) |
| Luxembourg to Slochteren | 250.74 mi (403.52 km) |
| Luxembourg to Sluis | 168.29 mi (270.83 km) |
| Luxembourg to Sneek | 237.23 mi (381.78 km) |
| Luxembourg to Soest | 181.34 mi (291.83 km) |
| Luxembourg to Someren | 123.76 mi (199.17 km) |
