| Lye to Spello | 945.60 mi (1,521.79 km) |
| Lye to Spilamberto | 811.02 mi (1,305.22 km) |
| Lye to Spilimbergo | 802.76 mi (1,291.91 km) |
| Lye to Spinea | 804.39 mi (1,294.55 km) |
| Lye to Spoleto | 958.19 mi (1,542.06 km) |
| Lye to Spoltore | 1,022.60 mi (1,645.71 km) |
| Lye to Spresiano | 794.41 mi (1,278.49 km) |
| Lye to Squinzano | 1,261.92 mi (2,030.87 km) |
| Lye to Statte | 1,225.30 mi (1,971.93 km) |
| Lye to Stezzano | 709.23 mi (1,141.39 km) |
| Lye to Strada | 869.96 mi (1,400.06 km) |
| Lye to Stradella | 726.37 mi (1,168.98 km) |
| Lye to Striano | 1,123.24 mi (1,807.67 km) |
| Lye to Subiaco | 1,015.45 mi (1,634.21 km) |
| Lye to Sulmona | 1,036.54 mi (1,668.15 km) |
