| Lyon to Sin-le-Noble | 327.86 mi (527.64 km) |
| Lyon to Six-Fours-les-Plages | 189.98 mi (305.74 km) |
| Lyon to Soissons | 260.01 mi (418.45 km) |
| Lyon to Soisy-sous-Montmorency | 252.68 mi (406.65 km) |
| Lyon to Sollies-Pont | 187.18 mi (301.23 km) |
| Lyon to Somain | 325.70 mi (524.16 km) |
| Lyon to Sorgues | 121.04 mi (194.80 km) |
| Lyon to Sotteville-les-Rouen | 306.69 mi (493.58 km) |
| Lyon to Soyaux | 224.13 mi (360.71 km) |
| Lyon to Stains | 248.57 mi (400.03 km) |
| Lyon to Stiring-Wendel | 256.90 mi (413.44 km) |
| Lyon to Strasbourg | 238.04 mi (383.08 km) |
| Lyon to Sucy-en-Brie | 234.59 mi (377.54 km) |
| Lyon to Suresnes | 247.42 mi (398.19 km) |
| Lyon to Talant | 109.20 mi (175.74 km) |
