| Lyss to Santa Venerina | 760.81 mi (1,224.41 km) |
| Lyss to Santeramo in Colle | 638.96 mi (1,028.31 km) |
| Lyss to Santo Stefano di Magra | 237.11 mi (381.60 km) |
| Lyss to Santo Stino di Livenza | 272.48 mi (438.51 km) |
| Lyss to Sarezzo | 169.40 mi (272.63 km) |
| Lyss to Sarno | 564.27 mi (908.10 km) |
| Lyss to Saronno | 129.53 mi (208.45 km) |
| Lyss to Sarzana | 241.16 mi (388.10 km) |
| Lyss to Sassari | 442.50 mi (712.13 km) |
| Lyss to Sasso Marconi | 264.96 mi (426.41 km) |
| Lyss to Sassuolo | 241.56 mi (388.76 km) |
| Lyss to Sava | 688.06 mi (1,107.32 km) |
| Lyss to Saviano | 555.61 mi (894.16 km) |
| Lyss to Savigliano | 167.75 mi (269.96 km) |
| Lyss to Savignano sul Panaro | 253.38 mi (407.77 km) |
