| Lyss to Smolyan | 937.16 mi (1,508.22 km) |
| Lyss to Sofia | 838.86 mi (1,350.02 km) |
| Lyss to Sopot | 905.15 mi (1,456.70 km) |
| Lyss to Sozopol | 1,047.90 mi (1,686.43 km) |
| Lyss to Sredets | 1,026.74 mi (1,652.37 km) |
| Lyss to Stamboliyski | 911.35 mi (1,466.67 km) |
| Lyss to Stara Zagora | 952.92 mi (1,533.57 km) |
| Lyss to Svilengrad | 998.91 mi (1,607.58 km) |
| Lyss to Svishtov | 906.12 mi (1,458.25 km) |
| Lyss to Targovishte | 972.98 mi (1,565.86 km) |
| Lyss to Teteven | 875.11 mi (1,408.36 km) |
| Lyss to Troyan | 896.75 mi (1,443.18 km) |
| Lyss to Tryavna | 933.28 mi (1,501.98 km) |
| Lyss to Tutrakan | 954.82 mi (1,536.63 km) |
| Lyss to Varna | 1,035.99 mi (1,667.27 km) |
