| Madrid to Santarem | 276.70 mi (445.31 km) |
| Madrid to Santiago do Cacem | 314.64 mi (506.36 km) |
| Madrid to Santo Andre | 315.66 mi (508.01 km) |
| Madrid to Santo Tirso | 256.75 mi (413.20 km) |
| Madrid to Sao Bras de Alportel | 318.72 mi (512.94 km) |
| Madrid to Sao Felix da Marinha | 261.07 mi (420.16 km) |
| Madrid to Sao Joao da Madeira | 252.99 mi (407.15 km) |
| Madrid to Sao Joao de Ver | 256.65 mi (413.04 km) |
| Madrid to Sao Mamede de Infesta | 261.70 mi (421.16 km) |
| Madrid to Sao Pedro do Sul | 230.09 mi (370.30 km) |
| Madrid to Satao | 212.60 mi (342.15 km) |
| Madrid to Seia | 210.34 mi (338.51 km) |
| Madrid to Senhora da Hora | 264.14 mi (425.08 km) |
| Madrid to Serpa | 269.59 mi (433.87 km) |
| Madrid to Serta | 236.19 mi (380.11 km) |
