| Madrid to Roznava | 1,314.76 mi (2,115.91 km) |
| Madrid to Ruzomberok | 1,270.88 mi (2,045.28 km) |
| Madrid to Sabinov | 1,347.85 mi (2,169.15 km) |
| Madrid to Sal'a | 1,188.15 mi (1,912.15 km) |
| Madrid to Samorin | 1,160.68 mi (1,867.94 km) |
| Madrid to Senec | 1,168.92 mi (1,881.19 km) |
| Madrid to Senica | 1,178.59 mi (1,896.76 km) |
| Madrid to Sered' | 1,184.91 mi (1,906.93 km) |
| Madrid to Skalica | 1,176.73 mi (1,893.77 km) |
| Madrid to Smizany | 1,320.69 mi (2,125.45 km) |
| Madrid to Snina | 1,392.14 mi (2,240.43 km) |
| Madrid to Spisska Nova Ves | 1,322.11 mi (2,127.73 km) |
| Madrid to Stara L'ubovna | 1,334.60 mi (2,147.83 km) |
| Madrid to Stara Tura | 1,194.98 mi (1,923.14 km) |
| Madrid to Stropkov | 1,374.30 mi (2,211.72 km) |
