| Madridejos to Sacile | 927.16 mi (1,492.12 km) |
| Madridejos to Sala Consilina | 1,013.75 mi (1,631.48 km) |
| Madridejos to Salemi | 887.54 mi (1,428.36 km) |
| Madridejos to Salerno | 969.04 mi (1,559.53 km) |
| Madridejos to Salo | 830.42 mi (1,336.43 km) |
| Madridejos to Salsomaggiore Terme | 783.34 mi (1,260.66 km) |
| Madridejos to Saluzzo | 668.33 mi (1,075.57 km) |
| Madridejos to Salzano | 898.54 mi (1,446.05 km) |
| Madridejos to Samarate | 756.09 mi (1,216.80 km) |
| Madridejos to San Benedetto del Tronto | 934.85 mi (1,504.49 km) |
| Madridejos to San Biagio di Callalta | 914.40 mi (1,471.59 km) |
| Madridejos to San Bonifacio | 857.74 mi (1,380.39 km) |
| Madridejos to San Casciano in Val di Pesa | 812.77 mi (1,308.03 km) |
| Madridejos to San Cataldo | 955.81 mi (1,538.22 km) |
| Madridejos to San Cesareo | 870.17 mi (1,400.41 km) |
