| Madridejos to Spello | 874.98 mi (1,408.14 km) |
| Madridejos to Spilamberto | 823.47 mi (1,325.24 km) |
| Madridejos to Spilimbergo | 948.52 mi (1,526.50 km) |
| Madridejos to Spinea | 899.46 mi (1,447.54 km) |
| Madridejos to Spoleto | 872.81 mi (1,404.66 km) |
| Madridejos to Spoltore | 943.08 mi (1,517.74 km) |
| Madridejos to Spresiano | 911.12 mi (1,466.31 km) |
| Madridejos to Squinzano | 1,142.31 mi (1,838.37 km) |
| Madridejos to Statte | 1,097.21 mi (1,765.78 km) |
| Madridejos to Stezzano | 794.02 mi (1,277.85 km) |
| Madridejos to Strada | 817.72 mi (1,315.99 km) |
| Madridejos to Stradella | 760.94 mi (1,224.62 km) |
| Madridejos to Striano | 958.83 mi (1,543.09 km) |
| Madridejos to Subiaco | 886.30 mi (1,426.36 km) |
| Madridejos to Sulmona | 929.29 mi (1,495.54 km) |
