| Mainz to Santeramo in Colle | 755.68 mi (1,216.14 km) |
| Mainz to Santo Stefano di Magra | 409.56 mi (659.13 km) |
| Mainz to Santo Stino di Livenza | 357.84 mi (575.89 km) |
| Mainz to Sarezzo | 312.52 mi (502.95 km) |
| Mainz to Sarno | 703.68 mi (1,132.46 km) |
| Mainz to Saronno | 303.20 mi (487.96 km) |
| Mainz to Sarzana | 413.29 mi (665.12 km) |
| Mainz to Sassari | 639.73 mi (1,029.54 km) |
| Mainz to Sasso Marconi | 410.32 mi (660.35 km) |
| Mainz to Sassuolo | 393.37 mi (633.07 km) |
| Mainz to Sava | 800.82 mi (1,288.79 km) |
| Mainz to Saviano | 695.25 mi (1,118.90 km) |
| Mainz to Savigliano | 369.68 mi (594.95 km) |
| Mainz to Savignano sul Panaro | 401.49 mi (646.14 km) |
| Mainz to Savignano sul Rubicone | 451.12 mi (726.01 km) |
