| Mairena del Aljarafe to Cutrofiano | 1,317.93 mi (2,121.00 km) |
| Mairena del Aljarafe to Dalmine | 990.94 mi (1,594.76 km) |
| Mairena del Aljarafe to Deruta | 1,048.40 mi (1,687.24 km) |
| Mairena del Aljarafe to Desenzano del Garda | 1,024.63 mi (1,648.98 km) |
| Mairena del Aljarafe to Desio | 973.78 mi (1,567.15 km) |
| Mairena del Aljarafe to Dolianova | 837.23 mi (1,347.39 km) |
| Mairena del Aljarafe to Dolo | 1,090.50 mi (1,755.00 km) |
| Mairena del Aljarafe to Domodossola | 954.74 mi (1,536.50 km) |
| Mairena del Aljarafe to Dorgali | 865.81 mi (1,393.39 km) |
| Mairena del Aljarafe to Dueville | 1,073.60 mi (1,727.79 km) |
| Mairena del Aljarafe to Eboli | 1,154.11 mi (1,857.36 km) |
| Mairena del Aljarafe to Elmas | 829.47 mi (1,334.90 km) |
| Mairena del Aljarafe to Empoli | 994.04 mi (1,599.75 km) |
| Mairena del Aljarafe to Enna | 1,113.80 mi (1,792.49 km) |
| Mairena del Aljarafe to Eraclea | 1,121.79 mi (1,805.34 km) |
