| Mairena del Aljarafe to Sacile | 1,124.82 mi (1,810.22 km) |
| Mairena del Aljarafe to Sala Consilina | 1,181.58 mi (1,901.57 km) |
| Mairena del Aljarafe to Salemi | 1,031.93 mi (1,660.73 km) |
| Mairena del Aljarafe to Salerno | 1,138.97 mi (1,833.00 km) |
| Mairena del Aljarafe to Salo | 1,028.76 mi (1,655.63 km) |
| Mairena del Aljarafe to Salsomaggiore Terme | 980.07 mi (1,577.27 km) |
| Mairena del Aljarafe to Saluzzo | 867.15 mi (1,395.55 km) |
| Mairena del Aljarafe to Salzano | 1,095.39 mi (1,762.86 km) |
| Mairena del Aljarafe to Samarate | 955.84 mi (1,538.28 km) |
| Mairena del Aljarafe to San Benedetto del Tronto | 1,119.59 mi (1,801.80 km) |
| Mairena del Aljarafe to San Biagio di Callalta | 1,111.45 mi (1,788.70 km) |
| Mairena del Aljarafe to San Bonifacio | 1,054.94 mi (1,697.75 km) |
| Mairena del Aljarafe to San Casciano in Val di Pesa | 1,003.66 mi (1,615.24 km) |
| Mairena del Aljarafe to San Cataldo | 1,098.36 mi (1,767.64 km) |
| Mairena del Aljarafe to San Cesareo | 1,048.92 mi (1,688.08 km) |
