| Manchester to Eckington | 38.18 mi (61.45 km) |
| Manchester to Edgware | 152.95 mi (246.16 km) |
| Manchester to Edinburgh | 175.03 mi (281.68 km) |
| Manchester to Edmonton | 157.89 mi (254.10 km) |
| Manchester to Egg Buckland | 227.10 mi (365.49 km) |
| Manchester to Elgin | 291.17 mi (468.59 km) |
| Manchester to Elland | 21.78 mi (35.05 km) |
| Manchester to Ellesmere Port | 30.22 mi (48.63 km) |
| Manchester to Ellon | 268.61 mi (432.29 km) |
| Manchester to Eltham | 170.25 mi (274.00 km) |
| Manchester to Ely | 128.38 mi (206.60 km) |
| Manchester to Emsworth | 189.99 mi (305.76 km) |
| Manchester to Enfield | 155.55 mi (250.34 km) |
| Manchester to Enfield Lock | 155.99 mi (251.04 km) |
| Manchester to Englefield Green | 158.18 mi (254.57 km) |
