| Manchester to Saint Ives | 264.63 mi (425.88 km) |
| Manchester to Saint Neots | 119.44 mi (192.22 km) |
| Manchester to Sale | 4.96 mi (7.98 km) |
| Manchester to Salford | 1.98 mi (3.19 km) |
| Manchester to Salisbury | 167.58 mi (269.70 km) |
| Manchester to Saltash | 228.12 mi (367.13 km) |
| Manchester to Saltcoats | 180.47 mi (290.44 km) |
| Manchester to Sandbach | 23.58 mi (37.94 km) |
| Manchester to Sanderstead | 173.91 mi (279.88 km) |
| Manchester to Sandhurst | 159.29 mi (256.36 km) |
| Manchester to Sandiacre | 55.12 mi (88.70 km) |
| Manchester to Sandown | 200.56 mi (322.77 km) |
| Manchester to Sandridge | 142.83 mi (229.86 km) |
| Manchester to Sandy | 123.69 mi (199.06 km) |
| Manchester to Scarborough | 93.15 mi (149.91 km) |
