| Manchester to Stannington | 29.76 mi (47.89 km) |
| Manchester to Stansted Mountfitchet | 149.68 mi (240.89 km) |
| Manchester to Stanwell | 158.42 mi (254.95 km) |
| Manchester to Stapleford | 55.33 mi (89.05 km) |
| Manchester to Staveley | 39.72 mi (63.92 km) |
| Manchester to Stepney | 164.22 mi (264.29 km) |
| Manchester to Stevenage | 138.57 mi (223.01 km) |
| Manchester to Stevenston | 180.31 mi (290.18 km) |
| Manchester to Stirling | 194.26 mi (312.62 km) |
| Manchester to Stockport | 6.30 mi (10.14 km) |
| Manchester to Stocksbridge | 27.03 mi (43.50 km) |
| Manchester to Stockton-on-Tees | 84.19 mi (135.49 km) |
| Manchester to Stoke Gifford | 136.18 mi (219.17 km) |
| Manchester to Stoke-on-Trent | 33.22 mi (53.47 km) |
| Manchester to Stone | 40.23 mi (64.74 km) |
