| Manchester to Stonehaven | 240.77 mi (387.48 km) |
| Manchester to Stourbridge | 70.72 mi (113.82 km) |
| Manchester to Stowmarket | 162.11 mi (260.88 km) |
| Manchester to Stranraer | 149.33 mi (240.33 km) |
| Manchester to Stratford | 163.71 mi (263.47 km) |
| Manchester to Stratford-upon-Avon | 91.70 mi (147.57 km) |
| Manchester to Stratton Saint Margaret | 132.39 mi (213.06 km) |
| Manchester to Streatham | 167.53 mi (269.62 km) |
| Manchester to Street | 164.10 mi (264.10 km) |
| Manchester to Streetly | 64.13 mi (103.21 km) |
| Manchester to Stretford | 3.45 mi (5.56 km) |
| Manchester to Strood | 184.20 mi (296.44 km) |
| Manchester to Stroud | 119.91 mi (192.98 km) |
| Manchester to Sudbury | 155.73 mi (250.63 km) |
| Manchester to Sudbury | 159.11 mi (256.07 km) |
