| Mannheim to Sonsbeck | 172.87 mi (278.21 km) |
| Mannheim to Sonthofen | 159.58 mi (256.82 km) |
| Mannheim to Spaichingen | 98.34 mi (158.26 km) |
| Mannheim to Spelle | 203.61 mi (327.68 km) |
| Mannheim to Spenge | 182.79 mi (294.17 km) |
| Mannheim to Speyer | 11.74 mi (18.90 km) |
| Mannheim to Spiesen-Elversberg | 61.09 mi (98.31 km) |
| Mannheim to Spremberg | 296.83 mi (477.70 km) |
| Mannheim to Springe | 194.38 mi (312.82 km) |
| Mannheim to Sprockhovel | 140.42 mi (225.98 km) |
| Mannheim to Stade | 287.47 mi (462.64 km) |
| Mannheim to Stadtallendorf | 96.11 mi (154.67 km) |
| Mannheim to Stadthagen | 198.65 mi (319.69 km) |
| Mannheim to Stadtlohn | 185.86 mi (299.12 km) |
| Mannheim to Stahnsdorf | 288.07 mi (463.60 km) |
