| Manzanares el Real to Sangeorgiu de Mures | 1,463.63 mi (2,355.49 km) |
| Manzanares el Real to Sangeorz-Bai | 1,480.13 mi (2,382.04 km) |
| Manzanares el Real to Sannicolau Mare | 1,277.00 mi (2,055.14 km) |
| Manzanares el Real to Santana | 1,321.77 mi (2,127.18 km) |
| Manzanares el Real to Satu Mare | 1,402.26 mi (2,256.72 km) |
| Manzanares el Real to Scobinti | 1,584.98 mi (2,550.78 km) |
| Manzanares el Real to Scornicesti | 1,460.35 mi (2,350.20 km) |
| Manzanares el Real to Sebes | 1,417.22 mi (2,280.80 km) |
| Manzanares el Real to Seini | 1,419.81 mi (2,284.96 km) |
| Manzanares el Real to Sfantu-Gheorghe | 1,523.13 mi (2,451.24 km) |
| Manzanares el Real to Sibiu | 1,444.24 mi (2,324.27 km) |
| Manzanares el Real to Sighetu Marmatiei | 1,449.69 mi (2,333.05 km) |
| Manzanares el Real to Sighisoara | 1,476.99 mi (2,376.99 km) |
| Manzanares el Real to Simeria | 1,389.74 mi (2,236.56 km) |
| Manzanares el Real to Sinaia | 1,510.33 mi (2,430.64 km) |
