| Maryland Heights to Orangevale (California) | 1,649.92 mi (2,655.29 km) |
| Maryland Heights to Orchards (Washington) | 1,697.08 mi (2,731.19 km) |
| Maryland Heights to Orcutt (California) | 1,670.56 mi (2,688.51 km) |
| Maryland Heights to Oregon (Ohio) | 423.22 mi (681.10 km) |
| Maryland Heights to Oregon (Wisconsin) | 296.12 mi (476.56 km) |
| Maryland Heights to Oregon City (Oregon) | 1,698.14 mi (2,732.90 km) |
| Maryland Heights to Orem (Utah) | 1,133.94 mi (1,824.90 km) |
| Maryland Heights to Orinda (California) | 1,711.45 mi (2,754.31 km) |
| Maryland Heights to Orland Park (Illinois) | 242.60 mi (390.43 km) |
| Maryland Heights to Orlando (Florida) | 880.57 mi (1,417.14 km) |
| Maryland Heights to Ormond Beach (Florida) | 842.70 mi (1,356.19 km) |
| Maryland Heights to Oro Valley (Arizona) | 1,228.31 mi (1,976.78 km) |
| Maryland Heights to Oroville (California) | 1,659.30 mi (2,670.39 km) |
| Maryland Heights to Oshkosh (Wisconsin) | 379.61 mi (610.93 km) |
| Maryland Heights to Oskaloosa (Iowa) | 211.52 mi (340.40 km) |
