| Mayfield Heights to Shoreham-by-Sea | 3,737.70 mi (6,015.24 km) |
| Mayfield Heights to Shotley Bridge | 3,571.33 mi (5,747.50 km) |
| Mayfield Heights to Shrewsbury | 3,590.00 mi (5,777.54 km) |
| Mayfield Heights to Sidcup | 3,735.98 mi (6,012.47 km) |
| Mayfield Heights to Sidmouth | 3,622.72 mi (5,830.21 km) |
| Mayfield Heights to Sileby | 3,653.48 mi (5,879.71 km) |
| Mayfield Heights to Sittingbourne | 3,763.51 mi (6,056.79 km) |
| Mayfield Heights to Skegness | 3,698.29 mi (5,951.82 km) |
| Mayfield Heights to Skelmersdale | 3,568.40 mi (5,742.78 km) |
| Mayfield Heights to Skipton | 3,587.38 mi (5,773.33 km) |
| Mayfield Heights to Sleaford | 3,673.26 mi (5,911.54 km) |
| Mayfield Heights to Slough | 3,706.47 mi (5,964.99 km) |
| Mayfield Heights to Small Heath | 3,631.35 mi (5,844.09 km) |
| Mayfield Heights to Smethwick | 3,626.10 mi (5,835.65 km) |
| Mayfield Heights to Snaresbrook | 3,728.05 mi (5,999.71 km) |
