| Mayfield Heights to Elyria (Ohio) | 35.18 mi (56.62 km) |
| Mayfield Heights to Emeryville (California) | 2,166.30 mi (3,486.33 km) |
| Mayfield Heights to Emmaus (Pennsylvania) | 317.69 mi (511.28 km) |
| Mayfield Heights to Emporia (Kansas) | 808.58 mi (1,301.29 km) |
| Mayfield Heights to Encinitas (California) | 2,037.32 mi (3,278.76 km) |
| Mayfield Heights to Endicott (New York) | 280.40 mi (451.26 km) |
| Mayfield Heights to Endwell (New York) | 282.70 mi (454.96 km) |
| Mayfield Heights to Englewood (Colorado) | 1,238.17 mi (1,992.65 km) |
| Mayfield Heights to Englewood (Florida) | 1,006.30 mi (1,619.49 km) |
| Mayfield Heights to Englewood (New Jersey) | 391.09 mi (629.41 km) |
| Mayfield Heights to Englewood (Ohio) | 188.12 mi (302.75 km) |
| Mayfield Heights to Enid (Oklahoma) | 948.13 mi (1,525.86 km) |
| Mayfield Heights to Ennis (Texas) | 1,049.29 mi (1,688.67 km) |
| Mayfield Heights to Ensley (Florida) | 825.62 mi (1,328.71 km) |
| Mayfield Heights to Enterprise (Alabama) | 744.93 mi (1,198.84 km) |
