| Mechelen-aan-de-Maas to Oria | 923.26 mi (1,485.84 km) |
| Mechelen-aan-de-Maas to Oristano | 778.83 mi (1,253.41 km) |
| Mechelen-aan-de-Maas to Orta Nova | 820.25 mi (1,320.06 km) |
| Mechelen-aan-de-Maas to Orte | 668.73 mi (1,076.21 km) |
| Mechelen-aan-de-Maas to Ortona | 724.82 mi (1,166.48 km) |
| Mechelen-aan-de-Maas to Orvieto | 646.58 mi (1,040.57 km) |
| Mechelen-aan-de-Maas to Orzinuovi | 432.83 mi (696.58 km) |
| Mechelen-aan-de-Maas to Osimo | 633.83 mi (1,020.05 km) |
| Mechelen-aan-de-Maas to Ospitaletto | 426.13 mi (685.80 km) |
| Mechelen-aan-de-Maas to Ostuni | 908.49 mi (1,462.07 km) |
| Mechelen-aan-de-Maas to Ottaviano | 816.84 mi (1,314.58 km) |
| Mechelen-aan-de-Maas to Ovada | 459.91 mi (740.15 km) |
| Mechelen-aan-de-Maas to Ozieri | 736.55 mi (1,185.37 km) |
| Mechelen-aan-de-Maas to Paceco | 959.37 mi (1,543.95 km) |
| Mechelen-aan-de-Maas to Pachino | 1,090.03 mi (1,754.23 km) |
