| Mechelen-aan-de-Maas to Sala Consilina | 872.46 mi (1,404.09 km) |
| Mechelen-aan-de-Maas to Salemi | 974.59 mi (1,568.46 km) |
| Mechelen-aan-de-Maas to Salerno | 834.13 mi (1,342.40 km) |
| Mechelen-aan-de-Maas to Salo | 433.76 mi (698.07 km) |
| Mechelen-aan-de-Maas to Salsomaggiore Terme | 470.63 mi (757.41 km) |
| Mechelen-aan-de-Maas to Saluzzo | 446.57 mi (718.69 km) |
| Mechelen-aan-de-Maas to Salzano | 478.71 mi (770.41 km) |
| Mechelen-aan-de-Maas to Samarate | 397.68 mi (640.01 km) |
| Mechelen-aan-de-Maas to San Benedetto del Tronto | 675.75 mi (1,087.51 km) |
| Mechelen-aan-de-Maas to San Biagio di Callalta | 477.82 mi (768.97 km) |
| Mechelen-aan-de-Maas to San Bonifacio | 464.02 mi (746.77 km) |
| Mechelen-aan-de-Maas to San Casciano in Val di Pesa | 568.06 mi (914.20 km) |
| Mechelen-aan-de-Maas to San Cataldo | 1,018.15 mi (1,638.56 km) |
| Mechelen-aan-de-Maas to San Cesareo | 717.99 mi (1,155.50 km) |
| Mechelen-aan-de-Maas to San Dona di Piave | 486.32 mi (782.65 km) |
