| Mechelen-aan-de-Maas to Santeramo in Colle | 880.80 mi (1,417.50 km) |
| Mechelen-aan-de-Maas to Santo Stefano di Magra | 511.18 mi (822.66 km) |
| Mechelen-aan-de-Maas to Santo Stino di Livenza | 484.28 mi (779.37 km) |
| Mechelen-aan-de-Maas to Sarezzo | 423.09 mi (680.90 km) |
| Mechelen-aan-de-Maas to Sarno | 822.30 mi (1,323.36 km) |
| Mechelen-aan-de-Maas to Saronno | 401.40 mi (645.99 km) |
| Mechelen-aan-de-Maas to Sarzana | 515.13 mi (829.02 km) |
| Mechelen-aan-de-Maas to Sassari | 722.63 mi (1,162.96 km) |
| Mechelen-aan-de-Maas to Sasso Marconi | 523.38 mi (842.29 km) |
| Mechelen-aan-de-Maas to Sassuolo | 503.70 mi (810.63 km) |
| Mechelen-aan-de-Maas to Sava | 927.00 mi (1,491.87 km) |
| Mechelen-aan-de-Maas to Saviano | 813.74 mi (1,309.59 km) |
| Mechelen-aan-de-Maas to Savigliano | 447.53 mi (720.22 km) |
| Mechelen-aan-de-Maas to Savignano sul Panaro | 513.37 mi (826.19 km) |
| Mechelen-aan-de-Maas to Savignano sul Rubicone | 569.77 mi (916.95 km) |
