| Mechelen-aan-de-Maas to Savona | 479.80 mi (772.17 km) |
| Mechelen-aan-de-Maas to Scafati | 823.90 mi (1,325.94 km) |
| Mechelen-aan-de-Maas to Scalea | 912.79 mi (1,468.99 km) |
| Mechelen-aan-de-Maas to Scandiano | 499.06 mi (803.16 km) |
| Mechelen-aan-de-Maas to Scandicci | 562.03 mi (904.50 km) |
| Mechelen-aan-de-Maas to Schio | 447.75 mi (720.59 km) |
| Mechelen-aan-de-Maas to Sciacca | 999.79 mi (1,609.01 km) |
| Mechelen-aan-de-Maas to Scicli | 1,077.05 mi (1,733.34 km) |
| Mechelen-aan-de-Maas to Scordia | 1,047.51 mi (1,685.80 km) |
| Mechelen-aan-de-Maas to Scorze | 476.33 mi (766.57 km) |
| Mechelen-aan-de-Maas to Sedico | 446.07 mi (717.89 km) |
| Mechelen-aan-de-Maas to Sedriano | 409.38 mi (658.83 km) |
| Mechelen-aan-de-Maas to Segni | 731.14 mi (1,176.66 km) |
| Mechelen-aan-de-Maas to Segrate | 414.71 mi (667.42 km) |
| Mechelen-aan-de-Maas to Selargius | 828.45 mi (1,333.25 km) |
