| Mechelen-aan-de-Maas to Spilamberto | 509.92 mi (820.64 km) |
| Mechelen-aan-de-Maas to Spilimbergo | 469.71 mi (755.93 km) |
| Mechelen-aan-de-Maas to Spinea | 482.21 mi (776.04 km) |
| Mechelen-aan-de-Maas to Spoleto | 657.28 mi (1,057.80 km) |
| Mechelen-aan-de-Maas to Spoltore | 711.72 mi (1,145.41 km) |
| Mechelen-aan-de-Maas to Spresiano | 468.66 mi (754.24 km) |
| Mechelen-aan-de-Maas to Squinzano | 939.49 mi (1,511.96 km) |
| Mechelen-aan-de-Maas to Statte | 906.74 mi (1,459.26 km) |
| Mechelen-aan-de-Maas to Stezzano | 411.39 mi (662.08 km) |
| Mechelen-aan-de-Maas to Strada | 575.44 mi (926.07 km) |
| Mechelen-aan-de-Maas to Stradella | 440.95 mi (709.63 km) |
| Mechelen-aan-de-Maas to Striano | 821.07 mi (1,321.38 km) |
| Mechelen-aan-de-Maas to Subiaco | 717.56 mi (1,154.79 km) |
| Mechelen-aan-de-Maas to Sulmona | 730.52 mi (1,175.65 km) |
| Mechelen-aan-de-Maas to Surbo | 943.89 mi (1,519.04 km) |
