| Medford to Odessa (Texas) | 1,335.84 mi (2,149.83 km) |
| Medford to Ogden (Utah) | 565.66 mi (910.35 km) |
| Medford to Oildale (California) | 519.55 mi (836.14 km) |
| Medford to Ojus (Florida) | 2,655.84 mi (4,274.16 km) |
| Medford to Okemos (Michigan) | 1,940.54 mi (3,122.99 km) |
| Medford to Oklahoma City (Oklahoma) | 1,436.38 mi (2,311.63 km) |
| Medford to Okmulgee (Oklahoma) | 1,507.69 mi (2,426.39 km) |
| Medford to Olathe (Kansas) | 1,482.77 mi (2,386.29 km) |
| Medford to Old Jamestown (Missouri) | 1,715.25 mi (2,760.43 km) |
| Medford to Oldsmar (Florida) | 2,446.10 mi (3,936.62 km) |
| Medford to Olean (New York) | 2,246.96 mi (3,616.14 km) |
| Medford to Olive Branch (Mississippi) | 1,839.68 mi (2,960.69 km) |
| Medford to Olivehurst (California) | 235.11 mi (378.37 km) |
| Medford to Olney (Maryland) | 2,377.82 mi (3,826.73 km) |
| Medford to Olympia (Washington) | 325.06 mi (523.13 km) |
