| Medford to Oswego (Illinois) | 1,760.35 mi (2,833.01 km) |
| Medford to Oswego (New York) | 2,316.90 mi (3,728.68 km) |
| Medford to Otsego (Minnesota) | 1,463.61 mi (2,355.45 km) |
| Medford to Ottawa (Illinois) | 1,741.01 mi (2,801.88 km) |
| Medford to Ottawa (Kansas) | 1,466.37 mi (2,359.90 km) |
| Medford to Ottumwa (Iowa) | 1,564.87 mi (2,518.42 km) |
| Medford to Overland (Missouri) | 1,714.13 mi (2,758.62 km) |
| Medford to Overland Park (Kansas) | 1,489.49 mi (2,397.10 km) |
| Medford to Overlea (Maryland) | 2,400.40 mi (3,863.07 km) |
| Medford to Oviedo (Florida) | 2,497.26 mi (4,018.95 km) |
| Medford to Owasso (Oklahoma) | 1,496.66 mi (2,408.64 km) |
| Medford to Owatonna (Minnesota) | 1,488.50 mi (2,395.51 km) |
| Medford to Owensboro (Kentucky) | 1,902.15 mi (3,061.22 km) |
| Medford to Owings Mills (Maryland) | 2,385.55 mi (3,839.17 km) |
| Medford to Owosso (Michigan) | 1,948.02 mi (3,135.03 km) |
