| Medford to Santa Rosa (California) | 268.98 mi (432.88 km) |
| Medford to Santaquin (Utah) | 597.65 mi (961.83 km) |
| Medford to Santee (California) | 729.20 mi (1,173.53 km) |
| Medford to Sapulpa (Oklahoma) | 1,491.13 mi (2,399.74 km) |
| Medford to Saraland (Alabama) | 2,067.03 mi (3,326.57 km) |
| Medford to Sarasota (Florida) | 2,480.64 mi (3,992.21 km) |
| Medford to Sarasota Springs (Florida) | 2,485.28 mi (3,999.66 km) |
| Medford to Saratoga (California) | 352.96 mi (568.03 km) |
| Medford to Saratoga Springs (New York) | 2,456.05 mi (3,952.64 km) |
| Medford to Saratoga Springs (Utah) | 583.43 mi (938.95 km) |
| Medford to Sartell (Minnesota) | 1,433.73 mi (2,307.36 km) |
| Medford to Satellite Beach (Florida) | 2,545.26 mi (4,096.20 km) |
| Medford to Sauk Rapids (Minnesota) | 1,436.99 mi (2,312.61 km) |
| Medford to Sault Ste. Marie (Michigan) | 1,901.58 mi (3,060.30 km) |
| Medford to Savage (Minnesota) | 1,478.14 mi (2,378.83 km) |
