| Medford to Silver Firs (Washington) | 383.37 mi (616.97 km) |
| Medford to Silver Spring (Maryland) | 2,383.85 mi (3,836.43 km) |
| Medford to Silver Springs Shores (Florida) | 2,438.17 mi (3,923.85 km) |
| Medford to Silverdale (Washington) | 368.30 mi (592.72 km) |
| Medford to Silverton (Oregon) | 184.23 mi (296.48 km) |
| Medford to Simi Valley (California) | 600.22 mi (965.96 km) |
| Medford to Simpsonville (South Carolina) | 2,233.87 mi (3,595.07 km) |
| Medford to Sioux City (Iowa) | 1,344.42 mi (2,163.64 km) |
| Medford to Sioux Falls (South Dakota) | 1,318.52 mi (2,121.96 km) |
| Medford to Skokie (Illinois) | 1,784.87 mi (2,872.47 km) |
| Medford to Sleepy Hollow (New York) | 2,492.22 mi (4,010.85 km) |
| Medford to Slidell (Louisiana) | 2,004.16 mi (3,225.39 km) |
| Medford to Smithfield (North Carolina) | 2,409.99 mi (3,878.51 km) |
| Medford to Smithfield (Utah) | 566.12 mi (911.08 km) |
| Medford to Smithville (Missouri) | 1,484.64 mi (2,389.30 km) |
