| Medford to Smyrna (Delaware) | 2,447.65 mi (3,939.11 km) |
| Medford to Smyrna (Georgia) | 2,145.24 mi (3,452.44 km) |
| Medford to Smyrna (Tennessee) | 1,979.62 mi (3,185.89 km) |
| Medford to Snellville (Georgia) | 2,171.64 mi (3,494.91 km) |
| Medford to Snoqualmie (Washington) | 362.13 mi (582.80 km) |
| Medford to Snyder (Texas) | 1,368.14 mi (2,201.81 km) |
| Medford to Socastee (South Carolina) | 2,432.04 mi (3,913.99 km) |
| Medford to Socorro (Texas) | 1,173.21 mi (1,888.09 km) |
| Medford to Soddy-Daisy (Tennessee) | 2,069.16 mi (3,329.99 km) |
| Medford to Solana Beach (California) | 714.00 mi (1,149.08 km) |
| Medford to Soledad (California) | 415.13 mi (668.10 km) |
| Medford to Solon (Ohio) | 2,110.80 mi (3,397.00 km) |
| Medford to Somers Point (New Jersey) | 2,497.20 mi (4,018.85 km) |
| Medford to Somerset (Kentucky) | 2,047.17 mi (3,294.60 km) |
| Medford to Somerset (New Jersey) | 2,474.27 mi (3,981.96 km) |
