| Medford to University Place (Washington) | 337.34 mi (542.90 km) |
| Medford to Upland (California) | 633.69 mi (1,019.83 km) |
| Medford to Upper Arlington (Ohio) | 2,056.05 mi (3,308.90 km) |
| Medford to Upper Grand Lagoon (Florida) | 2,210.70 mi (3,557.78 km) |
| Medford to Upper Montclair (New Jersey) | 2,481.58 mi (3,993.72 km) |
| Medford to Urbana (Illinois) | 1,795.11 mi (2,888.95 km) |
| Medford to Urbana (Maryland) | 2,359.90 mi (3,797.89 km) |
| Medford to Urbana (Ohio) | 2,019.89 mi (3,250.69 km) |
| Medford to Urbandale (Iowa) | 1,486.55 mi (2,392.37 km) |
| Medford to Utica (New York) | 2,385.17 mi (3,838.57 km) |
| Medford to Uvalde (Texas) | 1,571.19 mi (2,528.59 km) |
| Medford to Vacaville (California) | 278.82 mi (448.72 km) |
| Medford to Vadnais Heights (Minnesota) | 1,490.88 mi (2,399.34 km) |
| Medford to Vail (Arizona) | 975.80 mi (1,570.40 km) |
| Medford to Valdosta (Georgia) | 2,310.14 mi (3,717.80 km) |
