| Mesagne to Santeramo in Colle | 56.49 mi (90.91 km) |
| Mesagne to Santo Stefano di Magra | 472.71 mi (760.75 km) |
| Mesagne to Santo Stino di Livenza | 440.20 mi (708.43 km) |
| Mesagne to Sarezzo | 519.49 mi (836.04 km) |
| Mesagne to Sarno | 167.65 mi (269.81 km) |
| Mesagne to Saronno | 563.03 mi (906.10 km) |
| Mesagne to Sarzana | 469.13 mi (754.99 km) |
| Mesagne to Sassari | 484.34 mi (779.47 km) |
| Mesagne to Sasso Marconi | 425.84 mi (685.32 km) |
| Mesagne to Sassuolo | 450.55 mi (725.08 km) |
| Mesagne to Sava | 16.81 mi (27.05 km) |
| Mesagne to Saviano | 173.56 mi (279.32 km) |
| Mesagne to Savigliano | 588.36 mi (946.87 km) |
| Mesagne to Savignano sul Panaro | 437.87 mi (704.68 km) |
| Mesagne to Savignano sul Rubicone | 367.92 mi (592.11 km) |
