| Mesagne to Somma Lombardo | 578.67 mi (931.27 km) |
| Mesagne to Somma Vesuviana | 177.37 mi (285.44 km) |
| Mesagne to Sommacampagna | 484.35 mi (779.48 km) |
| Mesagne to Sona | 486.47 mi (782.90 km) |
| Mesagne to Sondrio | 554.92 mi (893.05 km) |
| Mesagne to Sora | 231.69 mi (372.87 km) |
| Mesagne to Sorbolo | 475.85 mi (765.80 km) |
| Mesagne to Soresina | 517.09 mi (832.18 km) |
| Mesagne to Sorisole | 543.68 mi (874.98 km) |
| Mesagne to Sorrento | 179.80 mi (289.35 km) |
| Mesagne to Sorso | 483.28 mi (777.76 km) |
| Mesagne to Sortino | 278.06 mi (447.50 km) |
| Mesagne to Soverato Marina | 146.14 mi (235.19 km) |
| Mesagne to Sovicille | 386.08 mi (621.34 km) |
| Mesagne to Spello | 312.67 mi (503.19 km) |
