| Mesolongi to Setubal | 1,633.24 mi (2,628.44 km) |
| Mesolongi to Sever do Vouga | 1,588.01 mi (2,555.66 km) |
| Mesolongi to Silves | 1,625.97 mi (2,616.75 km) |
| Mesolongi to Sines | 1,638.45 mi (2,636.84 km) |
| Mesolongi to Sintra | 1,656.69 mi (2,666.19 km) |
| Mesolongi to Sobrado de Paiva | 1,581.54 mi (2,545.24 km) |
| Mesolongi to Sobral de Monte Agraco | 1,641.90 mi (2,642.38 km) |
| Mesolongi to Soure | 1,605.90 mi (2,584.44 km) |
| Mesolongi to Tabua | 1,572.24 mi (2,530.28 km) |
| Mesolongi to Tavira | 1,584.50 mi (2,550.01 km) |
| Mesolongi to Tomar | 1,597.76 mi (2,571.34 km) |
| Mesolongi to Tondela | 1,574.25 mi (2,533.51 km) |
| Mesolongi to Torre de Moncorvo | 1,522.08 mi (2,449.55 km) |
| Mesolongi to Torres Novas | 1,605.01 mi (2,583.01 km) |
| Mesolongi to Torres Vedras | 1,647.36 mi (2,651.16 km) |
