| Messina to Novi di Modena | 521.49 mi (839.26 km) |
| Messina to Novi Ligure | 572.75 mi (921.76 km) |
| Messina to Nuoro | 363.61 mi (585.17 km) |
| Messina to Occhiobello | 508.05 mi (817.63 km) |
| Messina to Oderzo | 547.18 mi (880.60 km) |
| Messina to Oggiono | 613.15 mi (986.78 km) |
| Messina to Olbia | 373.25 mi (600.69 km) |
| Messina to Oleggio | 622.81 mi (1,002.31 km) |
| Messina to Olgiate Comasco | 623.55 mi (1,003.50 km) |
| Messina to Olgiate Olona | 617.45 mi (993.70 km) |
| Messina to Omegna | 644.72 mi (1,037.57 km) |
| Messina to Opera | 594.00 mi (955.96 km) |
| Messina to Oppeano | 540.02 mi (869.08 km) |
| Messina to Orbassano | 626.43 mi (1,008.15 km) |
| Messina to Orbetello | 371.87 mi (598.47 km) |
