| Middelburg to Sacile | 556.09 mi (894.94 km) |
| Middelburg to Sala Consilina | 956.35 mi (1,539.09 km) |
| Middelburg to Salemi | 1,045.70 mi (1,682.89 km) |
| Middelburg to Salerno | 916.44 mi (1,474.87 km) |
| Middelburg to Salo | 515.52 mi (829.64 km) |
| Middelburg to Salsomaggiore Terme | 546.67 mi (879.79 km) |
| Middelburg to Saluzzo | 506.07 mi (814.45 km) |
| Middelburg to Salzano | 566.11 mi (911.06 km) |
| Middelburg to Samarate | 469.90 mi (756.23 km) |
| Middelburg to San Benedetto del Tronto | 760.77 mi (1,224.35 km) |
| Middelburg to San Biagio di Callalta | 566.49 mi (911.68 km) |
| Middelburg to San Bonifacio | 548.10 mi (882.08 km) |
| Middelburg to San Casciano in Val di Pesa | 645.86 mi (1,039.40 km) |
| Middelburg to San Cataldo | 1,092.49 mi (1,758.20 km) |
| Middelburg to San Cesareo | 796.93 mi (1,282.53 km) |
