| Middelburg to Savignano sul Rubicone | 653.42 mi (1,051.59 km) |
| Middelburg to Savona | 545.31 mi (877.59 km) |
| Middelburg to Scafati | 905.73 mi (1,457.64 km) |
| Middelburg to Scalea | 996.06 mi (1,603.01 km) |
| Middelburg to Scandiano | 577.73 mi (929.77 km) |
| Middelburg to Scandicci | 640.14 mi (1,030.21 km) |
| Middelburg to Schio | 533.26 mi (858.20 km) |
| Middelburg to Sciacca | 1,071.37 mi (1,724.21 km) |
| Middelburg to Scicli | 1,152.41 mi (1,854.63 km) |
| Middelburg to Scordia | 1,124.06 mi (1,809.00 km) |
| Middelburg to Scorze | 563.83 mi (907.40 km) |
| Middelburg to Sedico | 535.41 mi (861.66 km) |
| Middelburg to Sedriano | 482.22 mi (776.07 km) |
| Middelburg to Segni | 810.48 mi (1,304.35 km) |
| Middelburg to Segrate | 489.60 mi (787.93 km) |
