| Middle Valley to Senftenberg | 4,719.42 mi (7,595.17 km) |
| Middle Valley to Siegburg | 4,480.90 mi (7,211.31 km) |
| Middle Valley to Siegen | 4,510.34 mi (7,258.69 km) |
| Middle Valley to Sigmaringen | 4,646.04 mi (7,477.07 km) |
| Middle Valley to Simbach am Inn | 4,793.05 mi (7,713.67 km) |
| Middle Valley to Simmerath | 4,451.07 mi (7,163.30 km) |
| Middle Valley to Sindelfingen | 4,617.22 mi (7,430.69 km) |
| Middle Valley to Sinsheim | 4,595.34 mi (7,395.48 km) |
| Middle Valley to Sinzheim | 4,581.83 mi (7,373.74 km) |
| Middle Valley to Sinzig | 4,490.43 mi (7,226.65 km) |
| Middle Valley to Soest | 4,493.14 mi (7,231.02 km) |
| Middle Valley to Solingen | 4,465.30 mi (7,186.20 km) |
| Middle Valley to Soltau | 4,515.64 mi (7,267.22 km) |
| Middle Valley to Sommerda | 4,621.63 mi (7,437.80 km) |
| Middle Valley to Sondershausen | 4,605.45 mi (7,411.76 km) |
