| Middle Valley to Entroncamento | 4,094.55 mi (6,589.55 km) |
| Middle Valley to Ericeira | 4,060.60 mi (6,534.90 km) |
| Middle Valley to Ermezinde | 4,045.69 mi (6,510.91 km) |
| Middle Valley to Esmoriz | 4,048.53 mi (6,515.48 km) |
| Middle Valley to Espinho | 4,046.52 mi (6,512.24 km) |
| Middle Valley to Esposende | 4,026.54 mi (6,480.09 km) |
| Middle Valley to Estarreja | 4,056.64 mi (6,528.53 km) |
| Middle Valley to Estoril | 4,068.31 mi (6,547.31 km) |
| Middle Valley to Estremoz | 4,154.67 mi (6,686.29 km) |
| Middle Valley to Evora | 4,146.60 mi (6,673.30 km) |
| Middle Valley to Fafe | 4,058.38 mi (6,531.33 km) |
| Middle Valley to Falagueira | 4,075.46 mi (6,558.82 km) |
| Middle Valley to Famalicao | 4,042.31 mi (6,505.48 km) |
| Middle Valley to Fanzeres | 4,047.76 mi (6,514.24 km) |
| Middle Valley to Faro | 4,187.40 mi (6,738.97 km) |
