| Middleburg to Elyria (Ohio) | 782.62 mi (1,259.51 km) |
| Middleburg to Emeryville (California) | 2,357.73 mi (3,794.41 km) |
| Middleburg to Emmaus (Pennsylvania) | 808.86 mi (1,301.74 km) |
| Middleburg to Emporia (Kansas) | 997.88 mi (1,605.93 km) |
| Middleburg to Encinitas (California) | 2,082.54 mi (3,351.52 km) |
| Middleburg to Endicott (New York) | 893.39 mi (1,437.77 km) |
| Middleburg to Endwell (New York) | 895.53 mi (1,441.22 km) |
| Middleburg to Englewood (Colorado) | 1,461.76 mi (2,352.48 km) |
| Middleburg to Englewood (Florida) | 214.46 mi (345.14 km) |
| Middleburg to Englewood (New Jersey) | 870.92 mi (1,401.60 km) |
| Middleburg to Englewood (Ohio) | 691.56 mi (1,112.96 km) |
| Middleburg to Enid (Oklahoma) | 1,020.30 mi (1,642.02 km) |
| Middleburg to Ennis (Texas) | 884.19 mi (1,422.96 km) |
| Middleburg to Ensley (Florida) | 322.17 mi (518.48 km) |
| Middleburg to Enterprise (Alabama) | 250.45 mi (403.07 km) |
