| Middleburg to Superior (Colorado) | 1,476.78 mi (2,376.65 km) |
| Middleburg to Superior (Wisconsin) | 1,272.84 mi (2,048.43 km) |
| Middleburg to Surprise (Arizona) | 1,803.55 mi (2,902.53 km) |
| Middleburg to Susanville (California) | 2,278.51 mi (3,666.91 km) |
| Middleburg to Sussex (Wisconsin) | 968.92 mi (1,559.33 km) |
| Middleburg to Suwanee (Georgia) | 304.14 mi (489.47 km) |
| Middleburg to Swansea (Illinois) | 746.22 mi (1,200.93 km) |
| Middleburg to Sweetwater (Florida) | 309.47 mi (498.05 km) |
| Middleburg to Sweetwater (Texas) | 1,104.40 mi (1,777.35 km) |
| Middleburg to Sycamore (Illinois) | 907.41 mi (1,460.33 km) |
| Middleburg to Sylacauga (Alabama) | 335.34 mi (539.68 km) |
| Middleburg to Sylvania (Ohio) | 811.89 mi (1,306.61 km) |
| Middleburg to Syosset (New York) | 880.37 mi (1,416.83 km) |
| Middleburg to Syracuse (New York) | 952.13 mi (1,532.30 km) |
| Middleburg to Syracuse (Utah) | 1,846.84 mi (2,972.21 km) |
