| Middlesbrough to Orbetello | 1,010.62 mi (1,626.43 km) |
| Middlesbrough to Oria | 1,303.41 mi (2,097.63 km) |
| Middlesbrough to Oristano | 1,111.07 mi (1,788.09 km) |
| Middlesbrough to Orta Nova | 1,198.84 mi (1,929.34 km) |
| Middlesbrough to Orte | 1,039.92 mi (1,673.58 km) |
| Middlesbrough to Ortona | 1,102.55 mi (1,774.39 km) |
| Middlesbrough to Orvieto | 1,017.37 mi (1,637.31 km) |
| Middlesbrough to Orzinuovi | 803.09 mi (1,292.45 km) |
| Middlesbrough to Osimo | 1,011.82 mi (1,628.37 km) |
| Middlesbrough to Ospitaletto | 798.04 mi (1,284.31 km) |
| Middlesbrough to Ostuni | 1,288.77 mi (2,074.08 km) |
| Middlesbrough to Ottaviano | 1,191.40 mi (1,917.37 km) |
| Middlesbrough to Ovada | 815.10 mi (1,311.78 km) |
| Middlesbrough to Ozieri | 1,075.53 mi (1,730.89 km) |
| Middlesbrough to Paceco | 1,316.69 mi (2,119.01 km) |
