| Middlesbrough to Sacile | 846.81 mi (1,362.80 km) |
| Middlesbrough to Sala Consilina | 1,249.17 mi (2,010.35 km) |
| Middlesbrough to Salemi | 1,332.90 mi (2,145.09 km) |
| Middlesbrough to Salerno | 1,209.15 mi (1,945.94 km) |
| Middlesbrough to Salo | 808.31 mi (1,300.85 km) |
| Middlesbrough to Salsomaggiore Terme | 838.18 mi (1,348.92 km) |
| Middlesbrough to Saluzzo | 788.26 mi (1,268.57 km) |
| Middlesbrough to Salzano | 858.19 mi (1,381.12 km) |
| Middlesbrough to Samarate | 760.28 mi (1,223.55 km) |
| Middlesbrough to San Benedetto del Tronto | 1,053.53 mi (1,695.49 km) |
| Middlesbrough to San Biagio di Callalta | 857.99 mi (1,380.80 km) |
| Middlesbrough to San Bonifacio | 840.89 mi (1,353.28 km) |
| Middlesbrough to San Casciano in Val di Pesa | 937.71 mi (1,509.09 km) |
| Middlesbrough to San Cataldo | 1,381.82 mi (2,223.82 km) |
| Middlesbrough to San Cesareo | 1,088.92 mi (1,752.44 km) |
