| Middlesbrough to Santa Venerina | 1,398.42 mi (2,250.53 km) |
| Middlesbrough to Santeramo in Colle | 1,260.29 mi (2,028.24 km) |
| Middlesbrough to Santo Stefano di Magra | 874.91 mi (1,408.03 km) |
| Middlesbrough to Santo Stino di Livenza | 864.82 mi (1,391.79 km) |
| Middlesbrough to Sarezzo | 796.17 mi (1,281.31 km) |
| Middlesbrough to Sarno | 1,197.21 mi (1,926.72 km) |
| Middlesbrough to Saronno | 766.30 mi (1,233.23 km) |
| Middlesbrough to Sarzana | 878.95 mi (1,414.53 km) |
| Middlesbrough to Sassari | 1,057.64 mi (1,702.11 km) |
| Middlesbrough to Sasso Marconi | 896.38 mi (1,442.59 km) |
| Middlesbrough to Sassuolo | 874.97 mi (1,408.12 km) |
| Middlesbrough to Sava | 1,307.00 mi (2,103.42 km) |
| Middlesbrough to Saviano | 1,188.58 mi (1,912.83 km) |
| Middlesbrough to Savigliano | 791.10 mi (1,273.16 km) |
| Middlesbrough to Savignano sul Panaro | 885.65 mi (1,425.32 km) |
