| Middlesbrough to Savignano sul Rubicone | 946.25 mi (1,522.84 km) |
| Middlesbrough to Savona | 831.30 mi (1,337.86 km) |
| Middlesbrough to Scafati | 1,198.37 mi (1,928.59 km) |
| Middlesbrough to Scalea | 1,288.86 mi (2,074.22 km) |
| Middlesbrough to Scandiano | 869.96 mi (1,400.07 km) |
| Middlesbrough to Scandicci | 932.10 mi (1,500.07 km) |
| Middlesbrough to Schio | 825.85 mi (1,329.07 km) |
| Middlesbrough to Sciacca | 1,358.85 mi (2,186.86 km) |
| Middlesbrough to Scicli | 1,442.27 mi (2,321.11 km) |
| Middlesbrough to Scordia | 1,414.62 mi (2,276.61 km) |
| Middlesbrough to Scorze | 855.87 mi (1,377.39 km) |
| Middlesbrough to Sedico | 826.50 mi (1,330.12 km) |
| Middlesbrough to Sedriano | 772.79 mi (1,243.69 km) |
| Middlesbrough to Segni | 1,102.59 mi (1,774.44 km) |
| Middlesbrough to Segrate | 780.92 mi (1,256.76 km) |
