| Middlesbrough to Spello | 1,016.90 mi (1,636.55 km) |
| Middlesbrough to Spilamberto | 882.32 mi (1,419.96 km) |
| Middlesbrough to Spilimbergo | 850.50 mi (1,368.74 km) |
| Middlesbrough to Spinea | 861.69 mi (1,386.75 km) |
| Middlesbrough to Spoleto | 1,030.73 mi (1,658.80 km) |
| Middlesbrough to Spoltore | 1,089.05 mi (1,752.66 km) |
| Middlesbrough to Spresiano | 848.81 mi (1,366.02 km) |
| Middlesbrough to Squinzano | 1,319.91 mi (2,124.19 km) |
| Middlesbrough to Statte | 1,286.51 mi (2,070.44 km) |
| Middlesbrough to Stezzano | 781.14 mi (1,257.12 km) |
| Middlesbrough to Strada | 945.49 mi (1,521.63 km) |
| Middlesbrough to Stradella | 804.82 mi (1,295.23 km) |
| Middlesbrough to Striano | 1,195.82 mi (1,924.49 km) |
| Middlesbrough to Subiaco | 1,090.12 mi (1,754.37 km) |
| Middlesbrough to Sulmona | 1,106.30 mi (1,780.42 km) |
