| Middlesbrough to Entroncamento | 1,096.86 mi (1,765.23 km) |
| Middlesbrough to Ericeira | 1,144.41 mi (1,841.75 km) |
| Middlesbrough to Ermezinde | 982.01 mi (1,580.39 km) |
| Middlesbrough to Esmoriz | 1,000.48 mi (1,610.12 km) |
| Middlesbrough to Espinho | 997.06 mi (1,604.61 km) |
| Middlesbrough to Esposende | 964.94 mi (1,552.92 km) |
| Middlesbrough to Estarreja | 1,013.08 mi (1,630.40 km) |
| Middlesbrough to Estoril | 1,161.17 mi (1,868.72 km) |
| Middlesbrough to Estremoz | 1,126.32 mi (1,812.64 km) |
| Middlesbrough to Evora | 1,149.32 mi (1,849.65 km) |
| Middlesbrough to Fafe | 960.75 mi (1,546.17 km) |
| Middlesbrough to Falagueira | 1,154.92 mi (1,858.67 km) |
| Middlesbrough to Famalicao | 968.33 mi (1,558.38 km) |
| Middlesbrough to Fanzeres | 985.06 mi (1,585.31 km) |
| Middlesbrough to Faro | 1,254.12 mi (2,018.31 km) |
