| Mission Viejo to Entroncamento | 5,660.25 mi (9,109.30 km) |
| Mission Viejo to Ericeira | 5,640.73 mi (9,077.88 km) |
| Mission Viejo to Ermezinde | 5,583.53 mi (8,985.82 km) |
| Mission Viejo to Esmoriz | 5,591.26 mi (8,998.27 km) |
| Mission Viejo to Espinho | 5,588.43 mi (8,993.70 km) |
| Mission Viejo to Esposende | 5,560.71 mi (8,949.10 km) |
| Mission Viejo to Estarreja | 5,602.33 mi (9,016.08 km) |
| Mission Viejo to Estoril | 5,652.28 mi (9,096.47 km) |
| Mission Viejo to Estremoz | 5,723.76 mi (9,211.50 km) |
| Mission Viejo to Evora | 5,722.30 mi (9,209.16 km) |
| Mission Viejo to Fafe | 5,589.62 mi (8,995.63 km) |
| Mission Viejo to Falagueira | 5,657.42 mi (9,104.74 km) |
| Mission Viejo to Famalicao | 5,576.58 mi (8,974.64 km) |
| Mission Viejo to Fanzeres | 5,586.32 mi (8,990.31 km) |
| Mission Viejo to Faro | 5,786.57 mi (9,312.59 km) |
