| Mitchell to Southern Pines (North Carolina) | 1,151.71 mi (1,853.49 km) |
| Mitchell to Southfield (Michigan) | 749.26 mi (1,205.82 km) |
| Mitchell to Southgate (Michigan) | 756.01 mi (1,216.67 km) |
| Mitchell to Southlake (Texas) | 746.00 mi (1,200.57 km) |
| Mitchell to Spanaway (Washington) | 1,200.47 mi (1,931.96 km) |
| Mitchell to Spanish Fork (Utah) | 741.83 mi (1,193.85 km) |
| Mitchell to Spanish Lake (Missouri) | 530.40 mi (853.60 km) |
| Mitchell to Spanish Springs (Nevada) | 1,147.54 mi (1,846.78 km) |
| Mitchell to Sparks (Nevada) | 1,151.95 mi (1,853.88 km) |
| Mitchell to Spartanburg (South Carolina) | 1,050.30 mi (1,690.29 km) |
| Mitchell to Spearfish (South Dakota) | 291.55 mi (469.20 km) |
| Mitchell to Speedway (Indiana) | 664.70 mi (1,069.73 km) |
| Mitchell to Spencer (Iowa) | 150.00 mi (241.40 km) |
| Mitchell to Spokane (Washington) | 971.95 mi (1,564.20 km) |
| Mitchell to Spokane Valley (Washington) | 962.78 mi (1,549.45 km) |
